A&O – CONSCIOUSNESS – Alternative Theories

ART & ORGANISM

THEORIES of CONSCIOUSNESS (ToCs)

Excerpts from recent research

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There may be no more powerful (and sometime poignant) example of “the blind men and the elephant” (see A&O Note) than its incarnation in “the scholars and consciousness”:  The most interesting of the multiple insights and hypotheses derived therefrom–often from very different perspectives and at many levels of organization–are very usefully itemized and characterized by Seth and Bayne (2022, listed below from their Table 1).   

When specific insights–detailed descriptions including those of physiological processes–are further considered by even the most superficial tenets of DEEP ethology, the developmental, ecological, evolutionary, analyses create a web of causes, consequences, and associations of a magisterial–almost cosmic beauty.   (then recall that “in the end, the wise often succumb to the beautiful”(Hölderlin)… the almost irresistible bias of “gorgeous trumps everything”).

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“There is now a wide range of candidate ToCs (Table 1 [below]).  Notably, instead of ToCs progressively being ‘ruled out’ as empirical data accumulate, they seem to be proliferating.   This proliferation has led to both attempts to integrate existing theories with each other (16) and the development of ‘adversarial collaborations’, in which proponents of competing theories agree in advance about whether the outcome of a proposed experiment will support or undermine their preferred theory (17).   However, there are significant challenges to both theory integration and adversarial collaboration, as we discuss. (READ Seth & Bayne 2022:439: https://www.nature.com/articles/s41583-022-00587-4)  (WATCH Seth being interviewed by Michael Schermer:  https://www.skeptic.com/michael-shermer-show/anil-seth-on-consciousness-self-volition/?mc_cid=3f29ca75a9&mc_eid=68c6eef77f)

 

 

Table 1 | A selection of [neurobiological] theories of consciousness [1]

(Theories includes those that are “either neurobiological in nature or potentially expressible in neurobiological terms” … selected by Seth & Bayne 2022) and excerpted from their paper.   (see “Box 2 (below) for other kinds of Theories of Consciousness [1])

(from Anil K. Seth & Tim Bayne (2022) Theories of consciousnessNature Reviews Neuroscience  23, 439–452 (2022). https://doi.org/10.1038/s41583-022-00587-4)

  • Theory, Primary claim, (Key refs) 
  • Higher- order theory (HOT) Consciousness depends on meta- representations of lower- order mental states (31,46)
  • Self- organizing metarepresentational theory: Consciousness is the brain’s (meta- representational) theory about itself (34,140)
  • Attended intermediate representation theory:  Consciousness depends on the attentional amplification of intermediate-level representations (141,142)
  • Global workspace theories (GWTs): Consciousness depends on ignition and broadcast within a neuronal global workspace where fronto-parietal cortical regions play a central, hub- like role ((47–49)
  • Integrated information theory (IIT): Consciousness is identical to the cause–effect structure of a physical substrate that specifies a maximum of irreducible integrated information (57,59,60)
  • Information closure theory:  Consciousness depends on non- trivial information closure with respect to an environment at particular coarse- grained scales (143)
  • Dynamic core theory. Consciousness depends on a functional cluster of neural activity combining high levels of dynamical integration and differentiation (144)
  • Neural Darwinism. Consciousness depends on re- entrant interactions reflecting a history of value- dependent learning events shaped by selectionist principles (145,146)
  • Local recurrency. Consciousness depends on local recurrent or re- entrant cortical processing and promotes learning (65,71)
  • Predictive processing. Perception depends on predictive inference of the causes of sensory signals;  provides a framework for systematically mapping neural mechanisms to aspects of consciousness (67,73,79)
  • Neuro- representationalism. Consciousness depends on multilevel neurally encoded predictive representations (84)
  • Active inference. Although views vary, in one version consciousness depends on temporally and counterfactually deep inference about self- generated actions (76; see also 91)
  • Beast machine theory Consciousness is grounded in allostatic control- oriented predictive inference (13,75,77; see also 90)
  • Neural subjective frame Consciousness depends on neural maps of the bodily state providing a first- person perspective (24)
  • Self comes to mind theory Consciousness depends on interactions between homeostatic routines and multilevel interoceptive maps, with affect and feeling at the core. (23,147)
  • Attention schema theory Consciousness depends on a neurally encoded model of the control of attention (148)
  • Multiple drafts model.   Consciousness depends on multiple (potentially inconsistent) representations rather than a single, unified representation that is available to a central system (149)
  • Sensorimotor theory.   Consciousness depends on mastery of the laws governing sensorimotor contingencies (88)
  • Unlimited associative learning.  Consciousness depends on a form of learning which enables an organism to link motivational value with stimuli or actions that are novel, compound and non- reflex inducing.  (150)
  • Dendritic integration theory. Consciousness depends on integration of top-down and bottom-up signalling at a cellular level (151)
  • Electromagnetic field theory.  Consciousness is identical to physically integrated, and causally active, information encoded in the brain’s global electromagnetic field (152)
  • Orchestrated objective reduction.  Consciousness depends on quantum computations within microtubules inside neurons (18)

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Box 2 | Other approaches: attention, learning and affect[1]

 

The landscape of theories of consciousness (ToCs) includes numerous other theoretical approaches in addition to those surveyed in this Review’s Table 1 (above). one approach focuses on attention. For example, Graziano’s attention schema theory associates conscious perception with a model of the control of attention(148). Another attention-based ToC is the attended intermediate representational theory. First proposed by Jackendoff(141) and defended in detail by Prinz(142), this theory holds that consciousness occurs when intermediate-level perceptual representations gain access to attention.

Other theoretical approaches focus on learning. These include the proposal by Jablonka and Ginsburg that minimal consciousness is underpinned by a form of associative learning they term ‘unlimited associative learning’. According to their proposal, this form of learning enables an organism to link motivational value with stimuli or actions that are novel, compound and non-reflex inducing(150). other learning-based theories overlap with some theories we have already described, such as Cleeremans’ version of higher-order theory (HoT)(34,140) and Lamme’s local recurrency account, which holds that recurrent signalling underpins consciousness in virtue of its role in learning(65). learning-based theories are also closely related to ‘selectionist’ approaches, which ground consciousness in evolutionary-like dynamics within and between neuronal populations(145,146).

Affect-based theories emphasize the brain’s role in physiological regulation as the basis for consciousness. These theories include Damasio’s proposal that consciousness depends on hierarchically nested representations of the organism’s physiological condition(147,170), and proposals that mix an affect-based emphasis with predictive processing to ground conscious experiences in control-oriented interoceptive predictions(13,77,90). Some affect-based theories deny that cortical mechanisms are necessary for con sciousness, instead locating the mechanisms of consciousness in the brainstem(171,172, although see ref.173).

 

 

 

REFERENCES 

[1] from SethBayne (2022) Theories of consciousnessNature Reviews Neuroscience (2022). https://doi.org/10.1038/s41583-022-00587-4)

 

  • Crick, F. & Koch, C. Towards a neurobiological theory of consciousness. Semin. Neurosci. 2, 263–275 (1990).  Google Scholar 
  • Metzinger, T. (ed.) Neural Correlates of Consciousness: Empirical and Conceptual Questions (MIT Press, 2000).
  • Koch, C., Massimini, M., Boly, M. & Tononi, G. Neural correlates of consciousness: progress and problems. Nat. Rev. Neurosci. 17, 307–321 (2016). CAS PubMed Article Google Scholar 
  • de Graaf, T. A., Hsieh, P. J. & Sack, A. T. The ‘correlates’ in neural correlates of consciousness. Neurosci. Biobehav. Rev. 36, 191–197 (2012). PubMed Article Google Scholar 
  • Aru, J., Bachmann, T., Singer, W. & Melloni, L. Distilling the neural correlates of consciousness. Neurosci. Biobehav. Rev. 36, 737–746 (2012). PubMed Article Google Scholar 
  • Tsuchiya, N., Wilke, M., Frassle, S. & Lamme, V. A. No-report paradigms: extracting the true neural correlates of consciousness. Trends Cogn. Sci. 19, 757–770 (2015). PubMed Article Google Scholar 
  • Klein, C., Hohwy, J. & Bayne, T. Explanation in the science of consciousness: from the neural correlates of consciousness (NCCs) to the difference-makers of consciousness (DMCs). Philos. Mind Scihttps://doi.org/10.33735/phimisci.2020.II.60 (2020). Article Google Scholar 
  • Michel, M. et al. Opportunities and challenges for a maturing science of consciousness. Nat. Hum. Behav. 3, 104–107 (2019). PubMed PubMed Central Article Google Scholar 
  • Seth, A. K. Consciousness: the last 50 years (and the next). Brain Neurosci. Adv. 2, 2398212818816019 (2018).  PubMed PubMed Central Article Google Scholar 
  • Seth, A. K. Explanatory correlates of consciousness: theoretical and computational challenges. Cogn. Comput. 1, 50–63 (2009). Article Google Scholar 
  • Searle, J. The Rediscovery of the Mind (MIT Press, 1992).
  • Varela, F. J. Neurophenomenology: a methodological remedy for the hard problem. J. Conscious. Stud. 3, 330–350 (1996). Google Scholar 
  • Seth, A. K. Being You: A New Science of Consciousness (Faber & Faber, 2021).  
  • Dennett, D. C. Welcome to strong illusionism. J. Conscious. Stud. 26, 48–58 (2019). Google Scholar  
  • Frankish, K. Illusionism as a Theory of Consciousness (Imprint Academic, 2017).  
  • Wiese, W. The science of consciousness does not need another theory, it needs a minimal unifying model. Neurosci. Conscious. 2020, niaa013 (2020).  PubMed PubMed Central Article Google Scholar 
  • Melloni, L., Mudrik, L., Pitts, M. & Koch, C. Making the hard problem of consciousness easier. Science 372, 911–912 (2021). This work sets out how an adversarial collaboration is planning to arbitrate between integrated information and global workspace ToCsCAS PubMed Article Google Scholar  
  • Hameroff, S. & Penrose, R. Consciousness in the universe: a review of the ‘Orch OR’ theory. Phys. Life Rev. 11, 39–78 (2014). PubMed Article Google Scholar 
  • Chalmers, D. J. & McQueen, K. in Quantum Mechanics and Consciousness (ed Gao, S.) (Oxford Univ. Press, 2022). 
  • Nagel, T. What is it like to be a bat? Philos. Rev. 83, 435–450 (1974). Article Google Scholar  
  • Bayne, T., Hohwy, J. & Owen, A. M. Are there levels of consciousness? Trends Cogn. Sci. 20, 405–413 (2016). This work challenges the common unidimensional notion of ‘level of consciousness’, outlining an alternative, richer, multidimensional account. PubMed Article Google Scholar  
  • Metzinger, T. Being No-One (MIT Press, 2003).
  • Damasio, A. Self Comes To Mind: Constructing the Conscious Brain (William Heinemann, 2010).
  • Park, H. D. & Tallon-Baudry, C. The neural subjective frame: from bodily signals to perceptual consciousness. Philos. Trans. R. Soc. Lond. B Biol. Sci. 369, 20130208 (2014). PubMed PubMed Central Article Google Scholar  
  • Bayne, T. The Unity of Consciousness (Oxford Univ. Press, 2010). 
  • Bayne, T. & Chalmers, D. J. in The Unity of Consciousness: Binding, Integration, and Dissociation (ed Cleeremans, A.) 23–58 (Oxford Univ. Press, 2003). 
  • Cummins, R. Functional analysis. J. Philos. 72, 741–765 (1975).  Article Google Scholar  
  • Blake, R., Brascamp, J. & Heeger, D. J. Can binocular rivalry reveal neural correlates of consciousness? Philos. Trans. R. Soc. Lond. B Biol. Sci. 369, 20130211 (2014).  PubMed PubMed Central Article Google Scholar  
  • Signorelli, C. M., Szczotka, J. & Prentner, R. Explanatory profiles of models of consciousness — towards a systematic classification. Neurosci. Conscious. 2021, niab021 (2021).  PubMed PubMed Central Article Google Scholar  
  • Lau, H. & Rosenthal, D. Empirical support for higher-order theories of conscious awareness. Trends Cogn. Sci. 15, 365–373 (2011). This work presents a summary of empirical evidence favouring higher-order ToCs. PubMed Article Google Scholar  
  • Rosenthal, D. Consciousness and Mind (Clarendon, 2005). 
  • Brown, R. The HOROR theory of phenomenal consciousness. Philos. Stud. 172, 1783–1794 (2015).  Article Google Scholar  
  • Cleeremans, A. Consciousness: the radical plasticity thesis. Prog. Brain Res. 168, 19–33 (2008). PubMed Article Google Scholar 
  • Cleeremans, A. et al. Learning to be conscious. Trends Cogn. Sci. 24, 112–123 (2020). PubMed Article Google Scholar 
  • Fleming, S. M. Awareness as inference in a higher-order state space. Neurosci. Conscious. 2020, niz020 (2020).  PubMed PubMed Central Article Google Scholar  
  • Lau, H. Consciousness, metacognition, and perceptual reality monitoring. Preprint at ArXiv https://doi.org/10.31234/osf.io/ckbyf (2020). Article Google Scholar  
  • Gershman, S. J. The generative adversarial brain. Front. Artif. Intell. https://doi.org/10.3389/frai.2019.00018 (2019). Article PubMed PubMed Central Google Scholar  
  • Cohen, M. A., Dennett, D. C. & Kanwisher, N. What is the bandwidth of perceptual experience? Trends Cogn. Sci. 20, 324–335 (2016). PubMed PubMed Central Article Google Scholar 
  • Haun, A. M., Tononi, G., Koch, C. & Tsuchiya, N. Are we underestimating the richness of visual experiences? Neurosci. Conscious. 3, 1–4 (2017). Google Scholar 
  • Odegaard, B., Chang, M. Y., Lau, H. & Cheung, S. H. Inflation versus filling-in: why we feel we see more than we actually do in peripheral vision. Philos. Trans. R. Soc. Lond. B Biol. Sci. https://doi.org/10.1098/rstb.2017.0345 (2018). Article PubMed PubMed Central Google Scholar 
  • LeDoux, J. E. & Brown, R. A higher-order theory of emotional consciousness. Proc. Natl Acad. Sci. USA 114, E2016–E2025 (2017). CAS PubMed PubMed Central Article Google Scholar 
  • Morrison, J. Perceptual confidence. Anal. Philos. 78, 99–147 (2016). Google Scholar 
  • Peters, M. A. K. Towards characterizing the canonical computations generating phenomenal experience. Preprint at PsyArXiv https://doi.org/10.31234/osf.io/bqfr6 (2021). Article Google Scholar 
  • Rosenthal, D. Consciousness and its function. Neuropsychologia 46, 829–840 (2008). PubMed Article Google Scholar 
  • Charles, L., Van Opstal, F., Marti, S. & Dehaene, S. Distinct brain mechanisms for conscious versus subliminal error detection. Neuroimage 73, 80–94 (2013). PubMed Article Google Scholar 
  • Brown, R., Lau, H. & LeDoux, J. E. Understanding the higher-order approach to consciousness. Trends Cogn. Sci. 23, 754–768 (2019). PubMed Article Google Scholar 
  • Baars, B. J. A Cognitive Theory of Consciousness (Cambridge Univ. Press, 1988).  
  • Dehaene, S. & Changeux, J. P. Experimental and theoretical approaches to conscious processing. Neuron 70, 200–227 (2011). CAS PubMed Article Google Scholar 
  • Mashour, G. A., Roelfsema, P., Changeux, J. P. & Dehaene, S. Conscious processing and the global neuronal workspace hypothesis. Neuron 105, 776–798 (2020). This work presents a summary of the neuronal GWT and its supporting evidence. CAS PubMed PubMed Central Article Google Scholar 
  • Dehaene, S., Sergent, C. & Changeux, J. P. A neuronal network model linking subjective reports and objective physiological data during conscious perception. Proc. Natl Acad. Sci. USA 100, 8520–8525 (2003). CAS PubMed PubMed Central Article Google Scholar 
  • Naccache, L. Why and how access consciousness can account for phenomenal consciousness. Philos. Trans. R. Soc. Lond. B Biol. Sci. https://doi.org/10.1098/rstb.2017.0357 (2018). Article PubMed PubMed Central Google Scholar 
  • Mashour, G. A. Cognitive unbinding: a neuroscientific paradigm of general anesthesia and related states of unconsciousness. Neurosci. Biobehav. Rev. 37, 2751–2759 (2013). PubMed Article Google Scholar 
  • Demertzi, A. et al. Human consciousness is supported by dynamic complex patterns of brain signal coordination. Sci. Adv. 5, eaat7603 (2019). This large empirical study of functional connectivity patterns across different global states of consciousness focuses on how these patterns relate to underlying structural connectivity. CAS PubMed PubMed Central Article Google Scholar 
  • Barttfeld, P. et al. Signature of consciousness in the dynamics of resting-state brain activity. Proc. Natl Acad. Sci. USA 112, 887–892 (2015). CAS PubMed PubMed Central Article Google Scholar 
  • Uhrig, L. et al. Resting-state dynamics as a cortical signature of anesthesia in monkeys. Anesthesiology 129, 942–958 (2018). PubMed Article Google Scholar 
  • Carruthers, P. Human and Animal Minds: The Consciousness Questions Laid to Rest (Oxford Univ. Press, 2019). Tononi, G. Consciousness as integrated information: a provisional manifesto. Biol. Bull. 215, 216–242 (2008). PubMed Article Google Scholar 
  • Tononi, G. Integrated information theory of consciousness: an updated account. Arch. Ital. Biol. 150, 293–329 (2012). CAS PubMed Google Scholar 
  • Tononi, G., Boly, M., Massimini, M. & Koch, C. Integrated information theory: from consciousness to its physical substrate. Nat. Rev. Neurosci. 17, 450–461 (2016). This work presents an account of the core claims and concepts of the integrated information ToC. CAS PubMed Article Google Scholar 
  • Oizumi, M., Albantakis, L. & Tononi, G. From the phenomenology to the mechanisms of consciousness: integrated information theory 3.0. PLoS Comput. Biol. 10, e1003588 (2014). PubMed PubMed Central Article CAS Google Scholar 
  • Tononi, G. & Koch, C. Consciousness: here, there and everywhere? Philos. Trans. R. Soc. Lond. B Biol. Sci. https://doi.org/10.1098/rstb.2014.0167 (2015). Article PubMed PubMed Central Google Scholar 
  • Haun, A. M. & Tononi, G. Why does space feel the way it does? Towards a principled account of spatial experienc. Entropy 21, 1160 (2019). PubMed Central Article Google Scholar 
  • Albantakis, L., Hintze, A., Koch, C., Adami, C. & Tononi, G. Evolution of integrated causal structures in animats exposed to environments of increasing complexity. PLoS Comput. Biol. 10, e1003966 (2014). PubMed PubMed Central Article Google Scholar 
  • Marshall, W., Gomez-Ramirez, J. & Tononi, G. Integrated information and state differentiation. Front. Psychol. 7, 926 (2016). PubMed PubMed Central Article Google Scholar 
  • Lamme, V. A. Towards a true neural stance on consciousness. Trends Cogn. Sci. 10, 494–501 (2006). PubMed Article Google Scholar 
  • Lamme, V. A. & Roelfsema, P. R. The distinct modes of vision offered by feedforward and recurrent processing. Trends Neurosci. 23, 571–579 (2000). CAS PubMed Article Google Scholar 
  • Hohwy, J. & Seth, A. K. Predictive processing as a systematic basis for identifying the neural correlates of consciousness. Philos. Mind Sci. 1, 3 (2020). Google Scholar 
  • Lamme, V. A., Super, H., Landman, R., Roelfsema, P. R. & Spekreijse, H. The role of primary visual cortex (V1) in visual awareness. Vis. Res. 40, 1507–1521 (2000). CAS PubMed Article Google Scholar 
  • Pascual-Leone, A. & Walsh, V. Fast backprojections from the motion to the primary visual area necessary for visual awareness. Science 292, 510–512 (2001). This early study uses transcranial magnetic stimulation to reveal a role for re-entrant activity in conscious visual perception in humans. CAS PubMed Article Google Scholar 
  • Boehler, C. N., Schoenfeld, M. A., Heinze, H. J. & Hopf, J. M. Rapid recurrent processing gates awareness in primary visual cortex. Proc. Natl Acad. Sci. USA 105, 8742–8747 (2008). CAS PubMed PubMed Central Article Google Scholar 
  • Lamme, V. A. How neuroscience will change our view on consciousness. Cogn. Neurosci. 1, 204–220 (2010). PubMed Article Google Scholar 
  • von Helmholtz, H. Handbuch der Phsyiologischen Optik [German] (Voss, 1867).
  • Clark, A. Whatever next? Predictive brains, situated agents, and the future of cognitive science. Behav. Brain Sci. 36, 181–204 (2013). This work presents a classic exposition of predictive processing and its relevance for perception, cognition and action. PubMed Article Google Scholar 
  • Friston, K. J. The free-energy principle: a unified brain theory? Nat. Rev. Neurosci. 11, 127–138 (2010). CAS PubMed Article Google Scholar 
  • Seth, A. K. in Open MIND (eds Windt, J. M. & Metzinger, T.) (MIND Group, 2015).
  • Friston, K. J. Am I self-conscious? (Or does self-organization entail self-consciousness?). Front. Psychol. 9, 579 (2018). PubMed PubMed Central Article Google Scholar 
  • Seth, A. K. & Tsakiris, M. Being a beast machine: the somatic basis of selfhood. Trends Cogn. Sci. 22, 969–981 (2018). PubMed Article Google Scholar 
  • Bruineberg, J., Dolega, K., Dewhurst, J. & Baltieri, M. The Emperor’s new Markov blankets. Behav. Brain Sci. https://doi.org/10.1017/S0140525X21002351 (2021). Article PubMed Google Scholar 
  • Hohwy, J. The Predictive Mind (Oxford Univ. Press, 2013).
  • Rao, R. P. & Ballard, D. H. Predictive coding in the visual cortex: a functional interpretation of some extra-classical receptive-field effects. Nat. Neurosci. 2, 79–87 (1999). CAS PubMed Article Google Scholar 
  • Teufel, C. & Fletcher, P. C. Forms of prediction in the nervous system. Nat. Rev. Neurosci. 21, 231–242 (2020). CAS PubMed Article Google Scholar
  • Friston, K. J., Daunizeau, J., Kilner, J. & Kiebel, S. J. Action and behavior: a free-energy formulation. Biol. Cybern. 102, 227–260 (2010). PubMed Article Google Scholar 
  • Parr, T. & Friston, K. J. Generalised free energy and active inference. Biol. Cybern. 113, 495–513 (2019). PubMed PubMed Central Article Google Scholar 
  • Pennartz, C. M. A. Consciousness, representation, action: the importance of being goal-directed. Trends Cogn. Sci. 22, 137–153 (2018). PubMed Article Google Scholar 
  • Williford, K., Bennequin, D., Friston, K. & Rudrauf, D. The projective consciousness model and phenomenal selfhood. Front. Psychol. 9, 2571 (2018). PubMed PubMed Central Article Google Scholar 
  • Hohwy, J. New directions in predictive processing. Mind Lang. 35, 209–223 (2020).  Article Google Scholar 
  • Seth, A. K. A predictive processing theory of sensorimotor contingencies: explaining the puzzle of perceptual presence and its absence in synesthesia. Cogn. Neurosci. 5, 97–118 (2014).  PubMed PubMed Central Article Google Scholar 
  • O’Regan, J. K. & Noë, A. A sensorimotor account of vision and visual consciousness. Behav. Brain Sci. 24, 939–973; discussion 973–1031 (2001). This primary description of the sensorimotor ToC argues that conscious perception is intimately related to action. PubMed Article Google Scholar 
  • Seth, A. K. Interoceptive inference, emotion, and the embodied self. Trends Cogn. Sci. 17, 565–573 (2013). This work presents a theoretical application of predictive processing to interoception and physiological regulation, relating this to experiences of emotion and selfhood. PubMed Article Google Scholar 
  • Barrett, L. F. The theory of constructed emotion: an active inference account of interoception and categorization. Soc. Cogn. Affect. Neurosci. 12, 1833 (2017). PubMed PubMed Central Article Google Scholar 
  • Solms, M. The hard problem of consciousness and the free energy principle. Front. Psychol. 9, 2714 (2018). PubMed Article Google Scholar 
  • Hohwy, J., Roepstorff, A. & Friston, K. Predictive coding explains binocular rivalry: an epistemological review. Cognition 108, 687–701 (2008). PubMed Article Google Scholar 
  • Parr, T., Corcoran, A. W., Friston, K. J. & Hohwy, J. Perceptual awareness and active inference. Neurosci. Conscious. 2019, niz012 (2019). PubMed PubMed Central Article Google Scholar 
  • Friston, K. J., FitzGerald, T., Rigoli, F., Schwartenbeck, P. & Pezzulo, G. Active inference: a process theory. Neural Comput. 29, 1–49 (2017). PubMed Article Google Scholar 
  • Boly, M. et al. Preserved feedforward but impaired top-down processes in the vegetative state. Science 332, 858–862 (2011). This neuroimaging study uses dynamic causal modelling to show that loss of consciousness in the vegetative state is associated with impaired top-down connectivity from frontal to temporal cortices. CAS PubMed Article Google Scholar 
  • Parr, T. & Friston, K. J. Working memory, attention, and salience in active inference. Sci. Rep. 7, 14678 (2017). PubMed PubMed Central Article CAS Google Scholar 
  • Chalmers, A. What is This Thing Called Science? (Queensland Univ. Press, 2013).
  • Godfrey-Smith, P. G. Theory and Reality: An Introduction to the Philosophy of Science 2nd edn (Univ. Chicago Press, 2021).
  • Lipton, P. Inference to the Best Explanation (Routledge, 2004).
  • Lau, H. & Passingham, R. E. Relative blindsight in normal observers and the neural correlate of visual consciousness. Proc. Natl Acad. Sci. USA 103, 18763–18768 (2006). This empirical study compares conscious and unconscious visual perception in humans, controlling for performance, and reveals differences in prefrontal activation. CAS PubMed PubMed Central Article Google Scholar 
  • van Vugt, B. et al. The threshold for conscious report: signal loss and response bias in visual and frontal cortex. Science 360, 537–542 (2018). This empirical study tracks the time course of neural signals in primate frontal cortex, showing that perceived stimuli elicit sustained activity, when compared with non-perceived stimuli. PubMed Article CAS Google Scholar 
  • Gaillard, R. et al. Converging intracranial markers of conscious access. PLoS Biol. 7, e61 (2009). PubMed Article CAS Google Scholar  
  • Panagiotaropoulos, T. I., Deco, G., Kapoor, V. & Logothetis, N. K. Neuronal discharges and gamma oscillations explicitly reflect visual consciousness in the lateral prefrontal cortex. Neuron 74, 924–935 (2012). CAS PubMed Article Google Scholar 
  • Kapoor, V. et al. Decoding internally generated transitions of conscious contents in the prefrontal cortex without subjective reports. Nat. Comm. 13, 1535 (2022). CAS Article Google Scholar 
  • Bellet, J. et al. Decoding rapidly presented visual stimuli from prefrontal ensembles without report nor post-perceptual processing. Neurosci. Conscious. 2022, niac005 (2022). PubMed PubMed Central Article Google Scholar 
  • Levinson, M., Podvalny, E., Baete, S. H. & He, B. J. Cortical and subcortical signatures of conscious object recognition. Nat. Commun. 12, 2930 (2021). CAS PubMed PubMed Central Article Google Scholar 
  • Boly, M. et al. Are the neural correlates of consciousness in the front or in the back of the cerebral cortex? Clinical and neuroimaging evidence. J. Neurosci. 37, 9603–9613 (2017).  CAS PubMed PubMed Central Article Google Scholar
  • Raccah, O., Block, N. & Fox, K. C. R. Does the prefrontal cortex play an essential role in consciousness? Insights from intracranial electrical stimulation of the human brain. J. Neurosci. 41, 2076–2087 (2021). CAS PubMed PubMed Central Article Google Scholar 
  • Odegaard, B., Knight, R. T. & Lau, H. Should a few null findings falsify prefrontal theories of conscious perception? J. Neurosci. 37, 9593–9602 (2017). CAS PubMed PubMed Central Article Google Scholar 
  • Brascamp, J., Blake, R. & Knapen, T. Negligible fronto-parietal BOLD activity accompanying unreportable switches in bistable perception. Nat. Neurosci. 18, 1672–1678 (2015). This empirical ‘no-report’ study shows that fronto-parietal activity does not track switches in perceptual dominance when subjective reports are not required. CAS PubMed PubMed Central Article Google Scholar 
  • Sergent, C. et al. Bifurcation in brain dynamics reveals a signature of conscious processing independent of report. Nat. Commun. 12, 1149 (2021). CAS PubMed PubMed Central Article Google Scholar 
  • Siclari, F. et al. The neural correlates of dreaming. Nat. Neurosci. 20, 872–878 (2017). CAS PubMed PubMed Central Article Google Scholar 
  • Wong, W. et al. The Dream Catcher experiment: blinded analyses failed to detect markers of dreaming consciousness in EEG spectral power. Neurosci. Conscious. 2020, niaa006 (2020). PubMed PubMed Central Article Google Scholar 
  • Block, N. Consciousness, accessibility, and the mesh between psychology and neuroscience. Behav. Brain Sci. 30, 481–548 (2007). This work argues that research in psychology and neuroscience shows that there is a real and not merely conceptual distinction between phenomenal consciousness (that is, experience) and cognitive access to phenomenal consciousness. PubMed Article Google Scholar 
  • Musgrave, A. in Relativism and Realism in Science (ed Nola, R.) 229–252 (Kluwer, 1988).
  • Song, C., Haun, A. M. & Tononi, G. Plasticity in the structure of visual space. eNeuro https://doi.org/10.1523/ENEURO.0080-17.2017 (2017). Article PubMed PubMed Central Google Scholar 
  • Marshel, J. H. et al. Cortical layer-specific critical dynamics triggering perception. Science https://doi.org/10.1126/science.aaw5202 (2019). Article PubMed PubMed Central Google Scholar 
  • Dembski, C., Koch, C. & Pitts, M. Perceptual awareness negativity: a physiological correlate of sensory consciousness. Trends Cogn. Sci. 25, 660–670 (2021). PubMed Article Google Scholar 
  • Sanchez, G., Hartmann, T., Fusca, M., Demarchi, G. & Weisz, N. Decoding across sensory modalities reveals common supramodal signatures of conscious perception. Proc. Natl Acad. Sci. USA 117, 7437–7446 (2020). CAS PubMed PubMed Central Article Google Scholar 
  • Sergent, C. The offline stream of conscious representations. Philos. Trans. R. Soc. Lond. B Biol. Sci. https://doi.org/10.1098/rstb.2017.0349 (2018). Article PubMed PubMed Central Google Scholar 
  • Michel, M. & Doerig, A. A new empirical challenge for local theories of consciousness. Mind Lang. https://doi.org/10.1111/mila.12319 (2021). Article Google Scholar 
  • Sergent, C. et al. Cueing attention after the stimulus is gone can retrospectively trigger conscious perception. Curr. Biol. 23, 150–155 (2013). This empirical study reveals that conscious perception of a stimulus can be influenced by events happening (hundreds of milliseconds) after the stimulus appeared (‘retro-perception’). CAS PubMed Article Google Scholar 
  • Roseboom, W. et al. Activity in perceptual classification networks as a basis for human subjective time perception. Nat. Commun. 10, 267 (2019). PubMed PubMed Central Article CAS Google Scholar 
  • Kent, L. & Wittmann, M. Special Issue: Consciousness science and its theories. Time consciousness: the missing link in theories of consciousness. Neurosci. Conscious. 2021, niab011 (2021). PubMed PubMed Central Article Google Scholar 
  • Husserl, E. Ideas: A General Introduction to Pure Phenomenology (Collier Books, 1963).
  • Yaron, I., Melloni, L., Pitts, M. & Mudrik, L. The ConTraSt database for analyzing and comparing empirical studies of consciousness theories. Nat. Hum. Behav. https://doi.org/10.1038/s41562-021-01284-5 (2022). This work presents an online resource of empirical studies of consciousness, organized with respect to different ToCsArticle PubMed Google Scholar 
  • Joglekar, M. R., Mejias, J. F., Yang, G. R. & Wang, X. J. Inter-areal balanced amplification enhances signal propagation in a large-scale circuit model of the primate cortex. Neuron 98, 222–234.e8 (2018).  CAS PubMed Article Google Scholar 
  • VanRullen, R. & Kanai, R. Deep learning and the global workspace theory. Trends Neurosci. 44, 692–704 (2021).  CAS PubMed Article Google Scholar 
  • Shea, N. & Frith, C. D. The global workspace needs metacognition. Trends Cogn. Sci. 23, 560–571 (2019).  PubMed Article Google Scholar 
  • Suzuki, K., Roseboom, W., Schwartzman, D. J. & Seth, A. K. A deep-dream virtual reality platform for studying altered perceptual phenomenology. Sci. Rep. 7, 15982 (2017).  PubMed PubMed Central Article CAS Google Scholar 
  • Vilas, M. G., Auksztulewicz, R. & Melloni, L. Active inference as a computational framework for consciousness. Rev. Philos. Psychol. https://doi.org/10.1007/s13164-021-00579-w (2021).  Article Google Scholar 
  • Browning, H. & Veit, W. The measurement problem in consciousness. Philos. Top. 48, 85–108 (2020).  Article Google Scholar 
  • Seth, A. K., Dienes, Z., Cleeremans, A., Overgaard, M. & Pessoa, L. Measuring consciousness: relating behavioural and neurophysiological approaches. Trends Cogn. Sci. 12, 314–321 (2008).  PubMed PubMed Central Article Google Scholar 
  • Michel, M. Calibration in consciousness science. Erkenntnis https://doi.org/10.1007/s10670-021-00383-z (2021).  Article Google Scholar 
  • Birch, J., Schnell, A. K. & Clayton, N. S. Dimensions of animal consciousness. Trends Cogn. Sci. 24, 789–801 (2020). PubMed PubMed Central Article Google Scholar 
  • Bayne, T., Seth, A. K. & Massimini, M. Are there islands of awareness? Trends Neurosci. 43, 6–16 (2020). This work presents an examination of the possibility of consciousness in isolated neural systems such as brain organoids, disconnected cortical hemispheres and ex cranio brains. CAS PubMed Article Google Scholar 
  • Dehaene, S., Lau, H. & Kouider, S. What is consciousness, and could machines have it? Science 358, 486–492 (2017).  CAS PubMed Article Google Scholar 
  • Hu, H., Cusack, R. & Naci, L. Typical and disrupted brain circuitry for conscious awareness in full-term and pre-term infants. (2021).
  • Owen, A. M. & Coleman, M. R. Detecting awareness in the vegetative state. Ann. N Y Acad. Sci. 9, 130–138 (2008).  Article Google Scholar 
  • Cleeremans, A. The radical plasticity thesis: how the brain learns to be conscious. Front. Psychol. 2, 86 (2011).  PubMed PubMed Central Article Google Scholar 
  • Jackendoff, R. Consciousness and the Computational Mind (MIT Press, 1987).
  • Prinz, J. The Conscious Brain: How Attention Engenders Experience (Oxford Univ. Press, 2012).
  • Chang, A. Y. C., Biehl, M., Yu, Y. & Kanai, R. Information closure theory of consciousness. Front. Psychol. 11, 1504 (2020).  PubMed PubMed Central Article Google Scholar 
  • Tononi, G. & Edelman, G. M. Consciousness and complexity. Science 282, 1846–1851 (1998). This work presents an early proposal of how measures of neural complexity might relate to phenomenological properties of (all) conscious experiencesCAS PubMed Article Google Scholar 
  • Edelman, G. M. Neural Darwinism: The Theory of Neuronal Group Selection (Basic Books 1987).
  • Edelman, G. M. The Remembered Present (Basic Books, 1989).
  • Damasio, A. The Feeling of What Happens: Body and Emotion in the Making of Consciousness (Harvest Books, 2000).
  • Graziano, M. S. A. The attention schema theory: a foundation for engineering artificial consciousness. Front. Robot. AI 4, 60 (2017).  Article Google Scholar 
  • Dennett, D. C. Consciousness Explained (Little, Brown, 1991).
  • Ginsburg, S. & Jablonka, E. The Evolution of the Sensitive Soul: Learning and the Origins of Consciousness (MIT Press, 2019).
  • Aru, J., Suzuki, M. & Larkum, M. E. Cellular mechanisms of conscious processing. Trends Cogn. Sci. 24, 814–825 (2020).  PubMed Article Google Scholar 
  • McFadden, J. Integrating information in the brain’s EM field: the cemi field theory of consciousness. Neurosci. Conscious. 2020, niaa016 (2020).  PubMed PubMed Central Article Google Scholar 
  • Fleming, S. M., Ryu, J., Golfinos, J. G. & Blackmon, K. E. Domain-specific impairment in metacognitive accuracy following anterior prefrontal lesions. Brain 137, 2811–2822 (2014).  PubMed PubMed Central Article Google Scholar 
  • Fox, K. C. R. et al. Intrinsic network architecture predicts the effects elicited by intracranial electrical stimulation of the human brain. Nat. Hum. Behav. 4, 1039–1052 (2020).  PubMed PubMed Central Article Google Scholar 
  • Dehaene, S. & Naccache, L. Towards a cognitive neuroscience of consciousness: basic evidence and a workspace framework. Cognition 79, 1–37 (2001).  CAS PubMed Article Google Scholar 
  • Sergent, C., Baillet, S. & Dehaene, S. Timing of the brain events underlying access to consciousness during the attentional blink. Nat. Neurosci. 8, 1391–1400 (2005).  CAS PubMed Article Google Scholar 
  • Mediano, P. A. M., Seth, A. K. & Barrett, A. B. Measuring integrated information: comparison of candidate measures in theory and simulation. Entropy 21, 17 (2019).  Article Google Scholar 
  • Casali, A. G. et al. A theoretically based index of consciousness independent of sensory processing and behavior. Sci. Transl. Med. 5, 198ra105 (2013). This empirical study shows that a measure of the complexity of the cortical response to transcranial magnetic stimulation distinguishes between a range of global conscious states, including disorders of consciousnessPubMed Article Google Scholar 
  • Luppi, A. I. et al. Consciousness-specific dynamic interactions of brain integration and functional diversity. Nat. Commun. 10, 4616 (2019).  PubMed PubMed Central Article CAS Google Scholar 
  • Hardstone, R. et al. Long-term priors influence visual perception through recruitment of long-range feedback. Nat. Commun. 12, 6288 (2021).  CAS PubMed PubMed Central Article Google Scholar 
  • de Lange, F. P., Heilbron, M. & Kok, P. How do expectations shape perception? Trends Cogn. Sci. 22, 764–779 (2018).  PubMed Article Google Scholar 
  • Melloni, L., Schwiedrzik, C. M., Muller, N., Rodriguez, E. & Singer, W. Expectations change the signatures and timing of electrophysiological correlates of perceptual awareness. J. Neurosci. 31, 1386–1396 (2011). This empirical study uses a perceptual hysteresis paradigm to show that expectations enhance and accelerate conscious perceptionCAS PubMed PubMed Central Article Google Scholar 
  • Pinto, Y., van Gaal, S., de Lange, F. P., Lamme, V. A. & Seth, A. K. Expectations accelerate entry of visual stimuli into awareness. J. Vis. 15, 13 (2015).  PubMed Article Google Scholar 
  • Chalmers, D. J. Facing up to the problem of consciousness. J. Conscious. Stud. 23, 200–219 (1995). This work presents the classic statement of the philosophical distinction between the ‘hard’ and ‘easy’ problems of consciousnessGoogle Scholar 
  • Levine, J. Materialism and qualia: the explanatory gap. Pac. Philos. Q. 64, 354–361 (1983).  Article Google Scholar 
  • Seth, A. K. The Real Problem (Aeon, 2016).
  • Balog, K. in The Oxford Handbook of Philosophy of Mind (eds Beckermann, A., McLaughlin, B. P., & Walter S.) 292–312 (Oxford Univ. Press, 2009).
  • Perry, J. Knowledge, Possibility, and Consciousness (MIT Press, 2001).
  • Varela, F. J., Thompson, E. & Rosch, E. The Embodied Mind: Cognitive Science and Human Experience (MIT Press, 1993).
  • Carvalho, G. B. & Damasio, A. Interoception and the origin of feelings: a new synthesis. Bioessays 43, e2000261 (2021).  PubMed Article Google Scholar 
  • Solms, M. The Hidden Spring: A Journey to the Source of Consciousness (Profile Books, 2021). 
  • Merker, B. Consciousness without a cerebral cortex: a challenge for neuroscience and medicine. Behav. Brain Sci. 30, 63–81; discussion 81–134.    (2007). PubMed Article Google Scholar 
  • Parvizi, J. & Damasio, A. Consciousness and the brainstem. Cognition 79, 135–160 (2001).  CAS PubMed Article Google Scholar 
  • Naber, M., Frassle, S. & Einhauser, W. Perceptual rivalry: reflexes reveal the gradual nature of visual awareness. PLoS ONE 6, e20910 (2011).  CAS PubMed PubMed Central Article Google Scholar 
  • Casarotto, S. et al. Stratification of unresponsive patients by an independently validated index of brain complexity. Ann. Neurol. 80, 718–729 (2016).  PubMed PubMed Central Article Google Scholar 
  • Shea, N. & Bayne, T. The vegetative state and the science of consciousness. Br. J. Philos. Sci. 61, 459–484 (2010).  PubMed Article Google Scholar  
  • Birch, J. The search for invertebrate consciousness. Noûs 56, 133–153 (2020).  PubMed PubMed Central Article Google Scholar 
  • Phillips, I. The methodological puzzle of phenomenal consciousness. Philos. Trans. R. Soc. Lond. B Biol. Sci. https://doi.org/10.1098/rstb.2017.0347 (2018). Article PubMed PubMed Central Google Scholar

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NEXUS

  • CONSCIOUSNESS.
  • ALTERNATIVE THEORIES of CONSCIOUSNESS.  Like the theories Blind wise men and the elephant, there are multiple theories–often complementary- of consciousness
  • CONNECTIONS CREATE, CONNECTIONS CHANGE (Phenomena have MEANING to the extent they are CONNECTED; they can alter the way in which cognitive processes (such as those in ART and SCIENCE) are coordinated). What about CONNECTIONS between INDIVIDUALS?
  • TEACHABLE MOMENTS, a PERFECT STORM: a SYNERGY of CIRCUMSTANCES that enables TRANSFORMATIVE LEARNING, an EXTRAORDINARY EXPERIENCE
  • CHANGE (all change involves connections and all changes in connection involve STRESS; the balance between disintegration and renewal) These have meaning to the extent they are COMMUNICATED.
  • COMMUNICATION (…involves CREATING CONNECTIONS within and between individuals) information must be transmitted.  When information is communicated within or between levels of organization (as in within or between individuals) and coordinated with change, learning occurs.   Communication involves transmitting and receiving information.  Sounds like “teaching” and “learning.”
  • TEACHING/LEARNING (learning involves coping with STRESS; resolving cognitive dissonance; error detection and correction))
  • TRANSFORMATIVE LEARNING (some learning experiences are deeply affecting and we move from KNOWING to REALIZING)
  • CONSCIOUSNESS, and some of its states relevant to ART; then

read the DEEP notes on consciousness, with a few ideas about Development, Ecology, Evolution, and Physiology.

Read about EXTRAORDINARY, transformative experiences . 

Read excerpts from Sacks “River of Conciousness”

A common shared experience that epitomizes the integration of several critical neurophysiological principles, DREAMING is a phenomenal state of consciousness with long cultural and artistic histories.

.